VP Translational Science

Job Title: Vice President, Translational Science – Immunology
Location: San Diego, CA

Company Overview:
A next-generation biotechnology company based in San Diego is leveraging a proprietary platform to discover and develop small molecule therapeutics targeting traditionally undruggable proteins. This innovative platform enables precision targeting of disease-relevant proteins with first-in-class mechanisms of action.

With a rapidly advancing pipeline in immunology, the organization is positioned to translate groundbreaking science into transformative clinical outcomes. The company culture values scientific rigor, creative problem-solving, and a highly collaborative environment.

Position Summary:
The organization is seeking an experienced and visionary Vice President, Translational Science – Immunology to lead the strategic and operational advancement of immunology programs from late discovery through IND-enabling studies and into early clinical development. This individual will act as a critical bridge between discovery and development teams, crafting data-driven translational strategies that support clinical entry and early proof of concept.

The ideal candidate will bring deep immunology expertise, a successful track record in translational science, and direct experience in moving therapeutics from preclinical stages into clinical trials in autoimmune or related diseases.

Key Responsibilities:

• Drive the translational strategy for immunology programs through IND and early clinical development.

• Lead design and execution of preclinical translational studies, including biomarker development and patient stratification approaches.

• Partner cross-functionally with Discovery, Preclinical Development, Clinical Development, Regulatory, and Program Management to align program goals and ensure seamless execution.

• Translate mechanistic insights into clinically actionable endpoints to support development decisions and regulatory interactions.

• Interpret complex data sets from various platforms (flow cytometry, transcriptomics, immunoassays, etc.) to guide program advancement.

• Represent Translational Science on cross-functional teams and senior leadership discussions.

• Build and mentor a high-performing translational research team.

• Engage with external collaborators, CROs, and advisors to extend translational capabilities.

Required Qualifications:

• Ph.D., M.D./Ph.D., or equivalent in Immunology, Cell Biology, or a related field.

• 15+ years of biotech or pharma experience, with a strong background in immunology and at least 8 years in a leadership

• Previous experience succesfully taking pre clinical products to clinical trial

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