Clinical Project Manager

An exciting opportunity has arisen for an experienced Clinical Project Manager to join an ambitious, early-stage gene therapy biotech as it builds its clinical operations function.

Working within a lean, growing team, you’ll take hands-on ownership of clinical studies from set-up through to close-out, with the opportunity to shape how clinical operations develops as the business and its pipeline expand.

The role

• Lead the selection, onboarding and management of CROs and specialist vendors, including RFPs, bid defence and contract input.
• Take ownership of assigned clinical trials from set-up through to close-out, ensuring delivery against timelines, budgets and quality expectations.
• Oversee study plans, regulatory and ethics submissions, essential documentation and trial milestones.
• Manage CRO performance and site delivery, working closely with investigators and external partners to maintain study quality.
• Coordinate study activities across clinical operations, including site readiness, supplies, data cleaning and close-out deliverables.
• Monitor budgets, forecasts, change orders and invoices, escalating risks and issues promptly.
• Contribute to the development of clinical SOPs, processes, templates and vendor governance as the function evolves.

We’re looking for:

• At least five years’ experience in clinical operations, with direct responsibility for live interventional trials.
• Experience selecting and managing CROs or clinical vendors, including RFPs and bid defence.
• Strong project management, organisational and stakeholder management skills.
• The confidence to work independently, make decisions within your remit and escalate issues when needed.
• A proactive, hands-on approach and a willingness to contribute beyond your immediate responsibilities.
• Excellent written and verbal communication skills.

Experience in any of the following would be particularly valuable:

• Gene therapy or other complex biologics.
• CNS or neurosurgical trials.
• Drug-device combination products.
• Surgical or late-phase interventional studies.