Head of DMPK
- Europe, United Kingdom
- Permanent
Senior scientific leadership position reporting to the CSO, leading DMPK across CRO services and internal drug discovery programs. Manage a multidisciplinary team of 8+ scientists, overseeing in vitro/in vivo PK, ADME, and bioanalytical activities across small molecules, peptides, and antibodies.
Key Responsibilities
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Provide scientific, strategic, and operational leadership for all DMPK activities
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Define and implement DMPK strategy supporting candidate selection, lead optimization, and preclinical development
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Lead and mentor team in PK/ADME study design, execution, analysis, and reporting
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Oversee CRO studies and internal programs ensuring quality, timely delivery, and partner satisfaction
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Serve as senior scientific interface with external partners and cross-functional teams
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Implement best practices, emerging technologies, and drive operational excellence
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Support business development and portfolio decisions with DMPK expertise
Essential Requirements
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PhD in Pharmaceutical Sciences, Pharmacology, Biochemistry, Chemistry, or related discipline
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6-8+ years industry experience in drug discovery/development with progressive leadership
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Expertise in PK, drug metabolism, ADME for small molecules and biologics
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Knowledge of PK/PD modeling for candidate selection and human exposure predictions
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Proven experience leading multidisciplinary teams in fast-paced environments
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Strong communication and ability to influence scientific decisions
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Experience managing both CRO services and internal R&D programs
What We Offer
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Competitive compensation based on experience + comprehensive benefits
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Collaborative, science-driven culture advancing innovative therapeutics
Location: Europe (remote)
Open to candidates eligible to work in Europe. Recruitment handled by Barrington James.