Head of DMPK

50192
  • Europe, United Kingdom
  • Permanent

Senior scientific leadership position reporting to the CSO, leading DMPK across CRO services and internal drug discovery programs. Manage a multidisciplinary team of 8+ scientists, overseeing in vitro/in vivo PK, ADME, and bioanalytical activities across small molecules, peptides, and antibodies.

Key Responsibilities

  • Provide scientific, strategic, and operational leadership for all DMPK activities

  • Define and implement DMPK strategy supporting candidate selection, lead optimization, and preclinical development

  • Lead and mentor team in PK/ADME study design, execution, analysis, and reporting

  • Oversee CRO studies and internal programs ensuring quality, timely delivery, and partner satisfaction

  • Serve as senior scientific interface with external partners and cross-functional teams

  • Implement best practices, emerging technologies, and drive operational excellence

  • Support business development and portfolio decisions with DMPK expertise

Essential Requirements

  • PhD in Pharmaceutical Sciences, Pharmacology, Biochemistry, Chemistry, or related discipline

  • 6-8+ years industry experience in drug discovery/development with progressive leadership

  • Expertise in PK, drug metabolism, ADME for small molecules and biologics

  • Knowledge of PK/PD modeling for candidate selection and human exposure predictions

  • Proven experience leading multidisciplinary teams in fast-paced environments

  • Strong communication and ability to influence scientific decisions

  • Experience managing both CRO services and internal R&D programs

What We Offer

  • Competitive compensation based on experience + comprehensive benefits

  • Collaborative, science-driven culture advancing innovative therapeutics

Location: Europe (remote)

Open to candidates eligible to work in Europe. Recruitment handled by Barrington James.


 

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